What exactly is Methyl Salicylate?

What exactly is Methyl Salicylate?

So, What Exactly Is Methyl Salicylate? An in depth Relative to Menthol

Methyl salicylate is really an ester that is natural executes really much like menthol. It really is commonly removed through vapor distillation of wintergreen leaves.

Relating to WebMD, methyl salicylate is situated in numerous ointments that are topical bought within the countertop for small joint aches or pains that are muscular. It could additionally be present in intimate services and products.

Therefore, what exactly is methyl salicylate and so what does it do? Both menthol and methyl salicylate are referred to as counterirritants, which means they cause cooling and sensations that are warming your skin. Counterirritants are mainly in charge of the title, and effect, known as “icy hot.”

A lot of these items shouldn’t be utilized on younger kids due to toxicity concerns, which we’ll explore later in this specific article.

Wintergreen Oil

You might nevertheless be wondering, what’s methyl salicylate? You will usually hear about wintergreen“oil or oil of wintergreen.” In accordance with a summary in the Journal of Alternative Complementary Medicine, methyl salicylate could be theprevalent ingredient in the oil and it is the purest form in the highest concentration you certainly will find. Based on an oil wintergreen podcast through the Royal Society of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the source that is same “…research has revealed that methyl salicylate is a component of a plant’s arsenal into the battle against pathogens and herbivores.”

Methyl salicylate smells extremely strongly of mint. Regardless of this, it will be noted that this ingredient will not belong within the mint genus of plant species. The burning sensation that is cold triggered through the TRPA1 channel. Methyl salicylate also activates the warmth channel TRPV1, that is the exact same channel regarded as triggered by chile peppers like capsaicin. Often, wintergreen oil is employed along with peppermint oil, because the two in tandem are thought to attenuate effects that are beneficial. Wintergreen oil is obtained by vapor distillation regarding the warmed, water-macerated leaves. Its often used interchangeably with sweet birch oil for flavoring meals and sweets.

Particular Products Which Utilize Methyl Salicylate

In accordance with drugs.com and goodguide.com, there are many items that have methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Soreness Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Residing Aloe Heat Lotion

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Excessive Strength Toothache relief

Young thieves that are living Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research posted in the Annals of Pharmacotherapy aimed to analyze the effectiveness of methyl salicylate in platelet inhibition when compared with aspirin. Platelet aggregation is yet another real method of talking about platelets clumping together within the bloodstream. This really is associated with bloodstream clotting.

This research utilized a little test of nine healthy males in the 30-46 a long time. All individuals got 162 mg of aspirin before a period that is washout then 5 g of 30% methyl salicylate preparation, both to be utilized on the anterior thighs. It was discovered that “both aspirin and MS produced statistically platelet that is significant; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There was clearly no difference that is large the 2. This shows that methyl salicylate works because effectively as aspirin for platelet aggregation, at least in healthy individuals.

Poisoning Fables and Issues

Investigation with this substance on the web shall expose a small number of situation reports of baby death. a few things should be noted about these. Such baby fatalities usually included the accidental swallowing of pure oil of wintergreen, the best concentration of methyl salicylate you will get.

This does not imply that overdoses can just only take place with ingestion; the substance may be consumed through your skin then incorporated into one’s system. Nonetheless, it absolutely was present in “Toxicity fables: the risk that is actual of Essential Oil Use,” published when you look at the International Journal of Aromatherapy, that, “if 10?ml of the 2.5% formula of wintergreen oil had been to be reproduced all at the same time to your epidermis and completely consumed, the dosage would represent the same quantity of salicylate present in a single 325?mg aspirin tablet.”

This is the reason oil of wintergreen is recognized as to be reasonably low-risk with few effects that are side. Nonetheless, it is strongly suggested that brand new moms and dads avoid getting the substance in the homely household, in the off-chance that a baby might get their or her arms upon it.

Also, it’s worth noting that methyl salicylate happens to be limited for use in cosmetics in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among many health great things about hemp seed oil constituents, you may also find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is most memorable being a health plus. The oil additionally contains 10-15% fiber, 20-25% protein, and 20-30% carbs.

A bioassay posted in “The structure of Hemp Seed Oil and its own Potentialas a source that is important of” reported in the methyl salicylate content of hemp seed oil. In addition they reported on the other side things contained in hemp seed oil, such as for instance cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

In Summary

Therefore let’s review what we’ve learned thus far:

Methyl salicylate cannabis oil is really an ester that is natural could be made organically or synthetically within the lab it is usually removed via vapor distillation of wintergreen leaves.

Oil of wintergreen may be the strongest, purest concentration of methyl salicylate.

USUALLY DO NOT INGEST oil of wintergreen.

Methyl salicylate can be present in over-the-counter services and products such as for instance toothache ointments and muscle tissue discomfort relievers to alleviate discomfort and produce a soothing feeling. It’s also often utilized in lower amounts to taste foods and sweets.

Wintergreen oil placed on your skin into the doses that are right represent the exact exact same quantity of salicylate present in one single 325 mg aspirin tablet.

Methyl salicylate works effortlessly against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace quantities.